|3D Model of an HIV Virus|
Edward M. Campbell, PhD, of Loyola University Health System senior researcher alleged, “Scientists have been trying to develop antiviral therapies for only about 75 years. Evolution has been playing this game for millions of years, and it has identified a point of intervention that we still know very little about.”
During the investigations, experts apparently identified six individual amino acids in a very rarely known region of the TRIM5a protein. These acids were affirmed to help the protein prevent viral infection. After being altered in human cells, these amino acids may make the protein lose its ability to block HIV-1 infection. The research is being carried forward to discover an amino acid, or combination of amino acids, that enable TRIM5a to destroy HIV. By assaying these vital amino acids, researchers can probably genetically engineer TRIM5a and make it more beneficial in humans.
|Rhesus Macaque Monkey (Wikipedia)|
The research will be published on September 15, 2010 issue of the journal Virology, and is now available online.